Dietary baking soda (NaHCO <sub>3</sub> ) therapy recovered urolithiasis-induced kidney injury in mice by inhibition of oxidative stress, pyroptosis, and inflammation through gut-kidney axis
In summary, NaHCO<sub>3</sub> exerted a protective effect <i>via</i> the gut-kidney axis in the urolithiasis mice model, suggesting its potential use as a dietary supplementation to be added to daily drinking water for the management of urolithiasis.
Authors
- Jun Luo (ORCID: https://orcid.org/0000-0003-3339-5566)
- Nengliang Duan
- Yunze Dong (ORCID: https://orcid.org/0000-0002-1742-6855)
- Yuchen Gao (ORCID: https://orcid.org/0000-0002-4493-6121)
- Hong-Min Zhou (ORCID: https://orcid.org/0000-0002-0724-5815)
- Xiangcheng Zhan
- Zhuifeng Guo (ORCID: https://orcid.org/0000-0003-0820-4748)
- Yanhua Chen (ORCID: https://orcid.org/0000-0001-6603-1975)
- Xiao Xu (ORCID: https://orcid.org/0000-0002-5033-7627)
- Bowen Chen (ORCID: https://orcid.org/0000-0003-3877-3837)
- Jingcheng Zhang (ORCID: https://orcid.org/0000-0002-6339-7661)
- Shuai Liu (ORCID: https://orcid.org/0000-0003-3104-5319)
- Xudong Yao
- Yunfei Xu (ORCID: https://orcid.org/0009-0002-3376-996X)
- Zhengchao Hong
- Tiancheng Xie
- Heng Cao (ORCID: https://orcid.org/0000-0002-4385-7958)
Institutions
- Tongji University (CN)
- Bengbu Medical College (CN)
- Fudan University (CN)
- Shanghai Tenth People's Hospital (CN)
Publication Details
- Journal
- Renal Failure
- Published
- 2025-06-29
- DOI
- https://doi.org/10.1080/0886022x.2025.2521456
- Citations
- 3
- Primary Topic
- Kidney Stones and Urolithiasis Treatments
- Type
- article
- Field-Weighted Citation Impact
- 4.56
Funders
- National Natural Science Foundation of China