Amniotic Band Syndrome with Supernumerary Nostril: A Case Report

Amniotic band syndrome is a rare congenital disorder resulting from the entrapment of fetal parts, particularly limbs or digits, in fibrous amniotic bands during intrauterine development. This condition is characterized by a wide spectrum of anomalies affecting multiple systems. Its estimated birth prevalence ranges from 1 in 1,200 to 1 in 15,000 live births. Supernumerary nostril—also referred to as triple or accessory nostril—is another rare congenital anomaly involving the presence of an additional nostril, which may or may not be associated with accessory cartilage. Typically unilateral and isolated, supernumerary nostrils can, in some cases, coexist with other congenital malformations. However, the co-occurrence of supernumerary nostril and ABS has not been documented in the literature to date. In this report, we present a rare case of a female patient born with a supernumerary nostril located above the left nostril in the context of amniotic band syndrome. This appears to be the first documented case of such an association. The aim of this report is to highlight the unusual combination of these two distinct congenital conditions and to contribute to the body of knowledge on the phenotypic variability of ABS. This case underscores the importance of thorough clinical evaluation in patients with congenital anomalies and suggests that rare associations may exist between seemingly unrelated malformations. Further research is needed to explore potential embryological links and to determine whether this association is incidental or part of a broader, yet unidentified, syndrome.