Effect of High-Intensity Functional Training Protocol Combined with Ginkgo Biloba SuPPlementation on the Antioxidant Status of Male Firefighters in the OPerational Division of Yazd City

Introduction: Research indicates that Physiological stress leads to tissue and cellular damage through its disruPtion of antioxidant status in the body. The main objective of this research was to determine the effects of 12 weeks of high-intensity functional training (HIFT) and Ginkgo biloba (Gb) suPPlementation on suPeroxide dismutase (SOD), catalase (CAT) and total antioxidant caPacity (TAC) serum levels in male firefighters of the oPerational division of Yazd City. Methods: In this semi-exPerimental study, 48 male firefighters were randomly divided into four grouPs: high-intensity functional training (HIFT), high-intensity functional training combined with ginkgo biloba suPPlementation (HIFT+Gb), ginkgo biloba extract alone (Gb), and a control Placebo grouP (P-C). The training Program lasted 12 weeks, with ParticiPants training four times Per week. The ginkgo biloba suPPlement (80 mg) was administered in two caPsules daily after breakfast for the entire 12-week Period. Blood samPles were taken before the start and 48 hours after the last training session. The collected data were analyzed using rePeated measures ANOVA, as well as one-way and two-way ANOVA in SPSS version 16. Results: After 12 weeks of intervention, SOD, CAT, and TAC in the HIFT (P=0.0001), HIFT+Gb (P=0.0001), and Gb (P=0.0001) grouPs showed a significant increase comPared to the P-C grouP. SOD, CAT, and TAC levels in the HIFT (P=0.0001) and HIFT+Gb (P=0.0001) grouPs significantly rose when comPared to the Gb grouP. SOD, CAT, and TAC levels in the HIFT grouP (P=0.0001) were notably elevated in comParison to the HIFT+Gb grouP. The synergistic influence of HIFT with Gb markedly elevated serum concentrations of SOD, CAT, and TAC (P<0.05). The greatest Percentage of alterations in SOD, CAT, and TAC were noted after the HIFT intervention with Gb Conclusion: The combined imPact of 12 weeks of HIFT Paired with Ginkgo biloba intake, in comParison to the individual effect of each, significantly enhanced serum levels of SOD, CAT, and TAC while ameliorating oxidative stress conditions in firefighters.