Unveiling the dual threat: combined elevated triglyceride-glucose index and intracranial arterial stenosis burden for enhanced stroke risk stratification

The synergistic combination of elevated TyG index and ICAS burden demonstrated superior prognostic value for 3-month stroke recurrence risk compared to either parameter independently, suggesting that concurrent assessment of insulin resistance (via TyG index) and vascular imaging biomarkers (via ICAS burden) may refine early risk stratification. This finding underscores the importance of integrating systemic metabolic dysfunction with structural cerebrovascular pathology to identify patients at heightened vulnerability during the critical post-stroke recovery window.