Synthesis of benzo[ <i>d</i> , <i>e</i> ]quinoline-spiro-succinimides <i>via</i> rhodium-catalyzed C–H activation/annulation of 1-naphthylamides with maleimides
This study unveils the first rhodium-catalyzed synthesis of benzo[<i>d</i>,<i>e</i>]quinoline-spiro-succinimides <i>via</i> C-H activation/annulation of 1-naphthylamides with maleimides, utilizing picolinamide as a directing group. This method boasts a broad substrate scope, excellent yields, and wide range of functional group tolerance. Mechanistic insights and promising photoluminescence are reported, demonstrating an efficient route to valuable all-carbon quaternary spirocyclic compounds.
Authors
- Mahesh A. Sonawane
- Nileshkumar B. Rathod (ORCID: https://orcid.org/0000-0002-9055-1919)
- Subhash Chandra Ghosh (ORCID: https://orcid.org/0000-0002-6528-1582)
- Dinesh Gopichand Thakur (ORCID: https://orcid.org/0000-0002-3084-1236)
- Sachinkumar D. Patel (ORCID: https://orcid.org/0000-0001-7486-4360)
- Raj N. Patel (ORCID: https://orcid.org/0000-0002-5303-527X)
- Dharmik M. Patel (ORCID: https://orcid.org/0000-0003-2787-8967)
Institutions
- Central Salt and Marine Chemicals Research Institute (IN)
- Academy of Scientific and Innovative Research (IN)
Publication Details
- Journal
- Organic & Biomolecular Chemistry
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1039/d5ob00825e
- Citations
- 7
- Primary Topic
- Catalytic C–H Functionalization Methods
- Type
- article
- Field-Weighted Citation Impact
- 6.55