Global Recruiting Patterns and Placebo Response Rates in Clinical Trials of Psoriatic Arthritis and Plaque Psoriasis
The global expansion of trial recruitment to less affluent countries may increase placebo rates in studies of psoriatic arthritis and plaque psoriasis. These higher placebo rates may reflect the higher perceived benefit in these countries, leading to regression to the mean after patients have been successfully enrolled.
Authors
- Shayesteh Khalili (ORCID: https://orcid.org/0000-0002-4008-7281)
- Brigitte Wildner (ORCID: https://orcid.org/0000-0002-0683-0801)
- A Jordanov
- Ahmed Shehab (ORCID: https://orcid.org/0000-0003-2553-3332)
- Andreas Kerschbaumer (ORCID: https://orcid.org/0000-0002-6685-8873)
- Josef S Smolen (ORCID: https://orcid.org/0000-0002-4302-8877)
- M. Steiner
- Daniel Aletaha
- Magdalena Maad
Institutions
- Vienna University of Economics and Business (AT)
- Medical University of Vienna (AT)
Publication Details
- Journal
- Arthritis & Rheumatology
- Published
- 2025-06-30
- DOI
- https://doi.org/10.1002/art.43302
- Citations
- 10
- Primary Topic
- Ethics in Clinical Research
- Type
- article
- Field-Weighted Citation Impact
- 18.79