<scp>PRDX6</scp> Drives Breast Cancer Progression Through Mitochondrial Biosynthesis and Oxidative Phosphorylation
PRDX6 maintains intracellular homeostasis by reducing ROS and promotes mitochondrial biogenesis and OXPHOS through TFAM-dependent and -independent pathways, driving BRCA progression.
Authors
- Danhua Zhang (ORCID: https://orcid.org/0000-0002-0586-4284)
- Mei Dai (ORCID: https://orcid.org/0000-0003-4475-4990)
Institutions
- Central South University (CN)
- Hunan Provincial Center for Disease Control and Prevention (CN)
- Second Xiangya Hospital of Central South University (CN)
Publication Details
- Journal
- Cancer Medicine
- Published
- 2025-06-30
- DOI
- https://doi.org/10.1002/cam4.71005
- Primary Topic
- Redox biology and oxidative stress
- Type
- article
- Field-Weighted Citation Impact
- 0.00