Research Progress on Mulberry Twig in the Treatment of Diabetic Peripheral Neuropathy

Diabetic Peripheral Neuropathy (DPN) is one of the most common and serious chronic complications of diabetes, severely impacting patients’ quality of life. Mulberry twig, as a traditional Chinese medicine, is frequently used in TCM clinical practices for treating limb meridian-related disorders. In recent years, numerous studies have demonstrated the potential value of mulberry twig and its active components in alleviating diabetic peripheral neuropathy. This paper reviews relevant domestic and international literature, covering the chemical composition of mulberry twig, its mechanisms in improving diabetic peripheral neuropathy, clinical applications, and future research directions. The aim is to provide a theoretical basis and reference for further research on mulberry twig as a treatment for DPN, promoting its development and application in the field of diabetic peripheral neuropathy management.