Present Progress and Perspectives on the Neurocognitive Mechanism of Juvenile Empathy Deficit in Conduct Disorders

品行障碍(Conduct Disorder, CD)是儿童青少年期最常见的精神心理障碍之一，具有预后性差、破坏性大和社会负担重的特点，是影响社会稳定的一大重要因素。在过去20年的研究中，研究者已充分肯定了共情能力在不同亚型品行障碍及反社会行为的发生和发展过程中的重要作用。本文主要以品行障碍共情缺陷(冷酷无情特质)为切入点探讨其认知神经机制，为其精确诊断和有效干预提供客观的神经生物学依据。Conduct disorder (CD) is one of the most common mental disorders in children and adolescents, which is characterized by poor prognosis, great destructiveness and heavy social burden, as well as a major influence factor of social instability. In the past 20 years, investigators have fully confirmed the important role of empathy in the formation of different conduct disorders and the occurrence and development of antisocial behavior. This present paper mainly focused on the neurocognitive mechanisms of empathy deficit (callous unemotional trait) in CD individuals, in order to provide objective neurobiological basis for accurate diagnosis and effective intervention of CD.