Progress in the Diagnosis and Treatment of Histoplasmosis

组织胞浆菌广泛存在于自然环境中，主要感染免疫功能低下的人群。该病通常引起肺部感染，严重时可发展为播散型，感染全身脏器。在我国主要流行于南方地区，发病率逐渐上升，且早期诊断及治疗较困难，为避免漏诊、误诊，现就组织胞浆菌病的流行病学、临床特征、诊断及治疗等诊治进展作一综述。Histoplasma is widely present in the natural environment and primarily infects immunocompromised individuals. The disease typically causes pulmonary infection, which can progress to the disseminated form in severe cases, involving multiple organs throughout the body. In China, it is mainly prevalent in southern regions, with an increasing incidence. Early diagnosis and treatment are challenging. To avoid missed diagnosis and misdiagnosis, this review summarizes the recent advances in the epidemiology, clinical features, diagnosis, and treatment of histoplasmosis.