Novel 2D/3D Hybrid Organoid System for High-Throughput Drug Screening in iPSC Cardiomyocytes
Thus, we have developed a novel 2D/3D hybrid organoid model that employs an integrated optical analysis platform to provide a reliable high-throughput method for studying cardiotoxicity, providing valuable data on calcium, contractility, and signal propagation.
Authors
- Haodi Wu (ORCID: https://orcid.org/0000-0002-7900-3073)
- Anita Saraf (ORCID: https://orcid.org/0000-0001-7096-7418)
- Basil Yaseen
- Jordann Lewis
Institutions
- University of Pittsburgh (US)
- Children's Hospital of Pittsburgh (US)
Publication Details
- Journal
- Therapeutics
- Published
- 2025-06-27
- DOI
- https://doi.org/10.3390/therapeutics2030011
- Citations
- 1
- Primary Topic
- 3D Printing in Biomedical Research
- Type
- article
- Field-Weighted Citation Impact
- 0.67