Metastatic Malignant Phaeochromocytoma in Ascitic Fluid: Cytological Diagnosis of a Rare Entity

In summary, a review of the literature showed that there are only isolated case reports of ruptured pheochromocytoma and to the best of our knowledge this report is the first to document metastatic phaeochromocytoma in peritoneal fluid within the cytopathology literature. Our case report emphasises the importance of clinical history in the context of the cytopathologic evaluation, and good cell block preparation, which allows the use of IHCs in challenging cases as it may lead to the discovery of unusual metastatic sources.

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Publication Details

Journal
Cytopathology
Published
2025-06-30
DOI
https://doi.org/10.1111/cyt.70003
Primary Topic
Adrenal and Paraganglionic Tumors
Type
article
Field-Weighted Citation Impact
0.00

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article

Metastatic Malignant Phaeochromocytoma in Ascitic Fluid: Cytological Diagnosis of a Rare Entity

Samer N. Khader, Sigfred Lajara, Scarlet Brockmoeller
Cytopathology
Adrenal and Paraganglionic Tumors
article

Metastatic Malignant Phaeochromocytoma in Ascitic Fluid: Cytological Diagnosis of a Rare Entity

Samer N. Khader, Sigfred Lajara, Scarlet Brockmoeller
article en

Abstract

In summary, a review of the literature showed that there are only isolated case reports of ruptured pheochromocytoma and to the best of our knowledge this report is the first to document metastatic phaeochromocytoma in peritoneal fluid within the cytopathology literature. Our case report emphasises the importance of clinical history in the context of the cytopathologic evaluation, and good cell block preparation, which allows the use of IHCs in challenging cases as it may lead to the discovery of unusual metastatic sources.

CytopathologyVol. 36(5)
University of Leeds (GB), St James's University Hospital (GB), Queen Elizabeth Hospital (GB), NIHR Newcastle Biomedical Research Centre (GB), University of Pittsburgh Medical Center (US), Newcastle University (GB)
University of Pittsburgh, National Institute for Health and Care Research, Department of Health and Social Care, Pathological Society of Great Britain and Ireland, Newcastle University, NIHR Newcastle Biomedical Research Centre
Openalex Percentile: Top 74%
Adrenal and Paraganglionic Tumors
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Metastatic Malignant Phaeochromocytoma in Ascitic Fluid: Cytological Diagnosis of a Rare Entity — Samer N. Khader, Sigfred Lajara, et al. · Cytopathology (2025) | TGRS Research Map | TGRS