MEDICAL SUPPORT IN THE COMPREHENSIVE TREATMENT OF GENERALIZED PERIODONTITIS (LITERATURE REVIEW)

The purpose of the study is to analyze the scientific literature on the means and approaches to drug support in the complex treatment of generalized periodontitis. Results of the study. Antimicrobial therapy aimed at eliminating the causative factors is a priority. General and local antibiotic therapy is widely used to eliminate the pathogen. Pathogenetic drug therapy involves the impact on the links of the pathological process, namely: the microcirculatory system, normalization of vascular and tissue permeability, improvement of metabolic processes, phagocytosis, reduction of hypoxia, intensity of free radical oxidation, reduction of acidosis, impact on specific and nonspecific defense, stimulation of osteogenesis. Steroidal and non-steroidal drugs that produce an antiinflammatory effect are widely used clinically. Sorbents have a significant sorption and antimicrobial effect through local application sorption. Sanogenetic drug therapy involves the use of general tonic and immunocorrective agents that increase the body's defenses, stimulate soft tissue regeneration, collagen and osteogenesis. Herbal remedies with various pharmacological effects are used: anti-inflammatory, antimicrobial, hyposensitizing, analgesic, etc. It is advisable to use drugs that contribute to the normalization of metabolic processes in complex treatment. Such substances are vitamins and trace elements. The use of algae, which have osteotropic, antioxidant, and immunostimulating effects, has become a new area of natural therapy. The use of osteotropic materials is important. It has been proven that soy products containing proteins, amino acids, vitamins, calcium, phosphorus, magnesium, iron, zinc and other trace elements, and lecithin have osteotropic activity. An effective increase in the body's nonspecific resistance is part of the complex treatment. In this regard, adaptogenic drugs of plant and animal origin are used, which enhance protein biosynthesis by modulating the body's defense systems. The prescription of medications should be adjusted in the presence of concomitant somatic pathology. Conclusion. The proposed drug regimens can only reduce the activity and progression of generalized periodontitis. Therefore, the problem remains relevant. It is promising to clarify and identify the key links of pathogenesis in each specific clinical case with individualization of the prescribed medication.