Adrenal Insufficiency Revealing Bilateral Adrenal Metastasis of a Lung Cancer: A Case Report

Adrenal insufficiency is a rare complication of adrenal metastasis and can be the first clinical manifestation of an underlying malignancy.Herein we report the case of a 34-yearsold male, with a history of heavy smoking, who presented to the emergency department after experiencing several weeks of weakness, rapid weight loss, skin pigmentation.The biological workup performed in emergency was in favor of adrenal insufficiency.The etiological investigation revealed a large lung mass which, after biopsy, turned out to be a lung adenocarcinoma.The lung cancer subsequently caused adrenal metastasis and therefore adrenal insufficiency.This case highlights the importance of considering adrenal metastasis as a possible cause of adrenal insufficiency in patients with a history of malignancy.

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Publication Details

Journal
Journal of Endocrine Surgery
Published
2025-01-01
DOI
https://doi.org/10.16956/jes.2025.25.2.85
Primary Topic
Adrenal and Paraganglionic Tumors
Type
article
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article

Adrenal Insufficiency Revealing Bilateral Adrenal Metastasis of a Lung Cancer: A Case Report

S. Wahbi, Samia Bentaleb, Hayat Aynaou, H. Salhi
Journal of Endocrine Surgery
Adrenal and Paraganglionic Tumors
article

Adrenal Insufficiency Revealing Bilateral Adrenal Metastasis of a Lung Cancer: A Case Report

S. Wahbi, Samia Bentaleb, Hayat Aynaou, H. Salhi
article en

Abstract

Adrenal insufficiency is a rare complication of adrenal metastasis and can be the first clinical manifestation of an underlying malignancy.Herein we report the case of a 34-yearsold male, with a history of heavy smoking, who presented to the emergency department after experiencing several weeks of weakness, rapid weight loss, skin pigmentation.The biological workup performed in emergency was in favor of adrenal insufficiency.The etiological investigation revealed a large lung mass which, after biopsy, turned out to be a lung adenocarcinoma.The lung cancer subsequently caused adrenal metastasis and therefore adrenal insufficiency.This case highlights the importance of considering adrenal metastasis as a possible cause of adrenal insufficiency in patients with a history of malignancy.

Journal of Endocrine SurgeryVol. 25(2)
Centre Hospitalier Universitaire Hassan II (MA), Sidi Mohamed Ben Abdellah University (MA)
Good health and well-being
Openalex Percentile: Top 74%
Adrenal and Paraganglionic Tumors
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