Regulation of Ferroptosis in Human Macrophages by Nitric Oxide Donors
DTPA, being an NO donor with a half-life of 3 h at 37°С, can be used to inhibit ferroptosis in THP-1 macrophages, which develops within 17-19 h. Therefore, there are mechanisms of prolongation of NO action in cells that should be studied to use NO donors for regulation of cellular ferroptosis.
Authors
- Timofey O. Klyucherev (ORCID: https://orcid.org/0000-0003-3751-9589)
- Peter Timashev (ORCID: https://orcid.org/0000-0001-7773-2435)
- Irina I. Vlasova (ORCID: https://orcid.org/0000-0003-1813-654X)
- Maria D. Yurkanova
- A A Zolotopup
Institutions
- Sechenov University (RU)
Publication Details
- Journal
- Sovremennye tehnologii v medicine
- Published
- 2025-06-30
- DOI
- https://doi.org/10.17691/stm2025.17.3.04
- Primary Topic
- Ferroptosis and cancer prognosis
- Type
- article
- Field-Weighted Citation Impact
- 0.00