OPTIMIZATION OF GOLDEN SNAIL (POMACEA CANALICULATA) MACERATION USING DIFFERENT SOLVENTS FOR ISOLATION OF TRITERPENOIDS

The golden snail is a type of mollusc pest that is very familiar to farmers in Indonesia.Utilizing the golden snail should be considered as an effort to reduce its impact as a plant pest and to increase its value in various uses.The golden snail is suspected to contain active triterpenoid compounds that have the potential to be used as a sex reversal agent in tilapia fish.These triterpenoid compounds can function as a synthetic hormone for 17-methyl testosterone, which has been banned due to its environmental unfriendliness.The treatment with different solvents aims to determine the effect of solvent types on the characteristics of golden snail meat extract and to identify the best solvent between methanol (polar) and hexane (nonpolar).Maceration was carried out for 7 x 24 hours with a ratio of 1:3 (1 golden snail meat; 3 solvent).The filtered extract from the sample with methanol as a solvent was higher compared to N-Hexane sample.Conversely, the residue from the methanol extraction was relatively less than the residue from the N-Hexane extraction.The yield of the golden snail extract using methanol was 0.83 0.36, while with N-Hexane it was 0.45 0.35.Golden snail meat has a highwater content.Methanol is capable of dissolving polar compounds and can interact with water molecules through hydrogen bonding, which results in the formation of hydrogen bonds.During extraction, hydrogen bonds that bind active components in the snail meat, which also has a high moisture content, are extracted and dissolved in the methanol solvent.On the other hand, hexane is a relatively non-reactive solvent and mostly reacts with acids, bases, and reducing agents.