Relationship between timing of achieving energy sufficiency and clinical outcomes in critically ill patients
The timing of achieving energy sufficiency (17.5 kcal/kg/day) is significantly associated with 60-day mortality in ICU patients. Combining RCS-derived inflection point (day 6) and intergroup comparisons, the optimal window for achieving energy sufficiency appears to be 4-6 days post-ICU admission, balancing metabolic stability and tissue repair needs while avoiding early overfeeding risks.
Authors
- Xiangfeng Yue
- Xiaoli Huang (ORCID: https://orcid.org/0000-0001-9628-5618)
- Quanjun Lyu (ORCID: https://orcid.org/0000-0003-2978-522X)
- Yongchun Li (ORCID: https://orcid.org/0000-0003-1938-377X)
- Xiaoxi Zhu (ORCID: https://orcid.org/0000-0003-0015-7182)
Institutions
- Zhengzhou University (CN)
- First Affiliated Hospital of Zhengzhou University (CN)
- Henan Provincial Center for Disease Control and Prevention (CN)
Publication Details
- Journal
- Frontiers in Nutrition
- Published
- 2025-06-30
- DOI
- https://doi.org/10.3389/fnut.2025.1565394
- Primary Topic
- Clinical Nutrition and Gastroenterology
- Type
- article
- Field-Weighted Citation Impact
- 0.00