CLU, FOS, and CXCL8 as diagnostic biomarkers for heart failure progression post-acute myocardial infarction: an integrated RNA-Seq and multi-machine learning study
Significantly upregulated DEGs, including CLU, FOS, and CXCL8, might be served as novel diagnostic biomarkers for HFpAMI, and dysregulated immune infiltration hinted possible the immune system intervention point in the setting of HFpAMI.
Authors
- Yongxia Wang (ORCID: https://orcid.org/0000-0002-2811-1146)
- Shiyang Xie (ORCID: https://orcid.org/0000-0001-7019-040X)
- Mingjun Zhu (ORCID: https://orcid.org/0000-0001-7646-6577)
- Jingjing Wei (ORCID: https://orcid.org/0000-0003-2020-8397)
- Peng Yu (ORCID: https://orcid.org/0000-0002-4623-8829)
- Yucai Hu
- Yilin Zhang (ORCID: https://orcid.org/0009-0007-4658-0265)
- Aolong Wang
- Xinlu Wang (ORCID: https://orcid.org/0000-0002-2622-7268)
- Bin Li (ORCID: https://orcid.org/0009-0008-3791-0936)
- Lijie Qiao (ORCID: https://orcid.org/0009-0009-1573-5812)
- Haitao Li (ORCID: https://orcid.org/0000-0001-9160-8334)
- Zhengwei Dong
Institutions
- Henan University of Traditional Chinese Medicine (CN)
- First Affiliated Hospital of Henan University of Traditional Chinese Medicine (CN)
- First Affiliated Hospital of Henan University (CN)
Publication Details
- Journal
- Frontiers in Cardiovascular Medicine
- Published
- 2025-06-30
- DOI
- https://doi.org/10.3389/fcvm.2025.1611668
- Citations
- 2
- Primary Topic
- Cardiac Fibrosis and Remodeling
- Type
- article
- Field-Weighted Citation Impact
- 2.78