Efficacy and safety of rimegepant for the acute treatment of migraine in Japan: A dose‐ranging, double‐blind, randomized controlled trial

This randomized trial was designed to test the effectiveness and safety of rimegepant for the acute treatment of migraine among adults in Japan. Results indicated that rimegepant was more effective than placebo, and the 75 mg dose was observed to be more effective than the 25 mg dose. These results are similar to previous findings from clinical studies in other countries, and suggest that rimegepant can help patients with migraine in Japan.

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Publication Details

Journal
Headache The Journal of Head and Face Pain
Published
2025-06-30
DOI
https://doi.org/10.1111/head.14994
Citations
5
Primary Topic
Migraine and Headache Studies
Type
article
Field-Weighted Citation Impact
7.36

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article

Efficacy and safety of rimegepant for the acute treatment of migraine in Japan: A dose‐ranging, double‐blind, randomized controlled trial

Fumihiko Sakai, Akio Arakawa, Takao Takeshima, Tomofumi Ishikawa et al.
5 citations
Headache The Journal of Head and Face Pain
Migraine and Headache Studies
7.36
article

Efficacy and safety of rimegepant for the acute treatment of migraine in Japan: A dose‐ranging, double‐blind, randomized controlled trial

Fumihiko Sakai, Akio Arakawa, Takao Takeshima, Tomofumi Ishikawa, Koichi Ikeda, Robert Croop, Terence Fullerton, Alexandra Thiry, Hiroki‎ Yoshimatsu, Yasuhiko Matsumori, Yuko Hoshino, Masako Kudo
article en
5 citations

Abstract

This randomized trial was designed to test the effectiveness and safety of rimegepant for the acute treatment of migraine among adults in Japan. Results indicated that rimegepant was more effective than placebo, and the 75 mg dose was observed to be more effective than the 25 mg dose. These results are similar to previous findings from clinical studies in other countries, and suggest that rimegepant can help patients with migraine in Japan.

Headache The Journal of Head and Face PainVol. 65(10)
Iwate Medical University (JP), Pfizer (United States) (US), Tominaga hospital (JP), Biohaven Pharmaceuticals (United States) (US), Pfizer (Japan) (JP)
Pfizer
Good health and well-being
Openalex Percentile: Top 3%
Migraine and Headache Studies
7.36
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Efficacy and safety of rimegepant for the acute treatment of migraine in Japan: A dose‐ranging, double‐blind, randomized controlled trial — Fumihiko Sakai, Akio Arakawa, et al. · Headache The Journal of Head and Face Pain (2025) | TGRS Research Map | TGRS