Calcitonin and procalcitonin measurement after cholecystokinin-2/gastrin receptor agonist stimulation in patients with advanced medullary thyroid cancer: results from the GRAN-T-MTC study
Procalcitonin concentrations after CP04 stimulation were highly correlated with calcitonin concentrations. Unlabeled CP04, if available commercially, may be considered an alternative stimulating agent in MTC patients, even in lower mass amounts. Further studies, including healthy controls, are required to prove this concept and calculate the diagnostic thresholds.
Authors
- Paulina Gaweda
- Alicja Hubalewska‐Dydejczyk (ORCID: https://orcid.org/0000-0001-5208-4689)
- Renata Mikołajczak (ORCID: https://orcid.org/0000-0002-6882-751X)
- Clemens Decristoforo (ORCID: https://orcid.org/0000-0003-0566-4036)
- Luka Ležaić (ORCID: https://orcid.org/0000-0002-1341-403X)
- Katja Zaletel (ORCID: https://orcid.org/0009-0004-8823-3489)
- Anna Skalniak (ORCID: https://orcid.org/0000-0001-7871-9347)
- Elwira Przybylik‐Mazurek (ORCID: https://orcid.org/0000-0003-0936-1403)
- Alide C Fröberg
- Petra Kolenc Peitl (ORCID: https://orcid.org/0000-0003-4746-6740)
- Bogdan Solnica (ORCID: https://orcid.org/0000-0002-0121-8154)
- Konrad Skórkiewicz (ORCID: https://orcid.org/0000-0002-0362-4500)
- Irene Johanna Virgolini (ORCID: https://orcid.org/0000-0001-7097-6170)
- Christine Rangger (ORCID: https://orcid.org/0000-0003-1167-9779)
- Danuta Fedak
- Katica Bajuk Studen (ORCID: https://orcid.org/0000-0002-2296-368X)
- Paola Anna Erba (ORCID: https://orcid.org/0000-0003-0058-7377)
- Marion de Jong (ORCID: https://orcid.org/0000-0003-2247-332X)
- Małgorzata Trofimiuk–Müldner (ORCID: https://orcid.org/0000-0001-5247-9760)
Institutions
- Jagiellonian University (PL)
- Innsbruck Medical University (AT)
- University of Ljubljana (SI)
- Ljubljana University Medical Centre (SI)
- Erasmus MC (NL)
- National Centre for Nuclear Research (PL)
- Krakow Cardiovascular Research Institute (PL)
- Azienda Ospedaliera Universitaria Pisana (IT)
- Erasmus University Rotterdam (NL)
Publication Details
- Journal
- Endokrynologia Polska
- Published
- 2025-06-24
- DOI
- https://doi.org/10.5603/ep.106662
- Primary Topic
- Lung Cancer Research Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- European Commission
- Bundesministerium für Bildung und Forschung
- Austrian Science Fund
- General Secretariat for Research and Technology
- Ministrstvo za Izobraževanje, Znanost in Šport
- Narodowe Centrum Badań i Rozwoju