Mitochondria-derived peptide MOTS-c restores mitochondrial respiration in type 2 diabetic heart
These findings demonstrate beneficial effects of MOTS-c treatment on glucose homeostasis and suggest a useful therapeutic option for diabetic-related cardiomyopathy and mitochondrial dysfunction.
Authors
- June‐Chiew Han (ORCID: https://orcid.org/0000-0002-6396-7628)
- Andrew J. Taberner (ORCID: https://orcid.org/0000-0002-0452-0308)
- Anthony J. Hickey
- Toan Pham (ORCID: https://orcid.org/0000-0002-6323-9217)
Institutions
- University of Auckland (NZ)
Publication Details
- Journal
- Frontiers in Physiology
- Published
- 2025-06-30
- DOI
- https://doi.org/10.3389/fphys.2025.1602271
- Citations
- 5
- Primary Topic
- GDF15 and Related Biomarkers
- Type
- article
- Field-Weighted Citation Impact
- 8.34
Funders
- National Heart Foundation of New Zealand
- Health Research Council of New Zealand
- Marsden Fund