Patients with a Resected Pancreatic Cystic Neoplasm: A Single Center 10-Year Experience

Objective: Pancreatic cystic neoplasia represents a challenging and complex spectrum of lesions within the pancreas and requires a detailed understanding of their biological behavior and clinical implications.We aimed to examine the demographic characteristics, imaging and histopathological features, and clinical outcomes of patients who underwent pancreatic surgery due to cystic neoplasms.Moreover the impact of sarcopenia and obesity on clinical outcomes was investigated.Methods: Patients who underwent pancreatic surgery with the preliminary diagnosis of pancreatic cystic neoplasia at the General Surgery Clinic of Kartal Dr. Ltfi Krdar City Hospital between 2010 and 2020 were retrospectively evaluated.The size, morphological features, location, and number of the cystic lesions were recorded.The presence of sarcopenia was determined by measuring the psoas muscle cross-sectional area at the L3 level with preoperative CT and calculating the psoas muscle index. Results:The number of patients included in the study was 23 and the average age of these patients was 59.4 (SD: 14.3).18 (78.3%) of the patients were women.The most common cyst type was mucinous cystic neoplasia (30.4%), followed by an adenoma (26%), ductal adenocarcinoma (26%) and IPMN (17.3%).The most common surgery was the Whipple procedure (56.5%).Sarcopenia was detected in 47.8% of the patients.Postoperative complications were seen in 6 (26%) patients. Conclusion:This study provides valuable information regarding pancreatic cystic neoplasms' pathological and clinical consequences.In particular, it is one of the few studies investigating the relationship between sarcopenia, obesity and pancreatic cystic neoplasms in the current literature.