Cerebroplacental Ratio and Perinatal Outcomes in Preterm Premature Rupture of Membranes

Objective:The aim of this study is to compare the relationship between cerebroplacental ratio (CPR) and adverse perinatal outcomes in pregnant women with preterm premature rupture of membranes (PPROM).Methods: This prospective observational study included pregnant women who were at 24-36 weeks' gestation, had a singleton pregnancy and were diagnosed with PPROM.CPR were analysed in two groups (<1 and >1).Birth indication, delivery method, birth weight and poor perinatal outcomes were recorded.Foetal compromise was used as one of the determinants of the labour decision.Foetal compromise was diagnosed in those with category 3 foetal heart rate trace based on the ACOG guideline.Results: Fetal compromise was significantly higher in the CPR of <1 group than in the CPR of >1 group (28.6 vs. 6.9%,p=0.006).No significant difference was observed between the low and high CPR groups in terms of birth weight (2140485.7 vs. 2225470.1,p=0.390) and 5th min APGAR scores (9 vs. 10, p=0.159).Neonatal intensive care needs were comparable between the two groups (40% vs. 30%, p=0.332). Conclusion:Low CPR in PPROM is associated with foetal compromise.Clinicians might consider to use CPR in determining the foetal status during follow-up of a PPROM pregnancy.