Engineered PAM-SPION Nanoclusters for Enhanced Cancer Therapy: Integrating Magnetic Targeting with pH-Responsive Drug Release
The integration of targeting antibodies, magnetic guidance, and a pH-responsive PAM coating creates a versatile theranostic platform with significantly enhanced drug delivery capabilities. The unexpected synergistic effect of the AMF pre-treatment represents a promising new approach for improving the therapeutic efficacy of nanoparticle-based cancer treatments.
Authors
- Κωνσταντίνα Παπαδιά
- Dimitra Tzavara
- Argiris Kolokithas‐Ntoukas (ORCID: https://orcid.org/0000-0001-8592-0380)
- Αθανάσιος Σκούρας (ORCID: https://orcid.org/0000-0003-4813-1627)
- Sophia G. Antimisiaris (ORCID: https://orcid.org/0000-0002-2312-5848)
Institutions
- University of Patras (GR)
- Regional Centre of Advanced Technologies and Materials (CZ)
- Palacký University Olomouc (CZ)
- Foundation for Research and Technology Hellas (GR)
Publication Details
- Journal
- Molecules
- Published
- 2025-06-28
- DOI
- https://doi.org/10.3390/molecules30132785
- Citations
- 4
- Primary Topic
- Nanoparticle-Based Drug Delivery
- Type
- article
- Field-Weighted Citation Impact
- 2.39