Detecting Diffusion-Weighted Imaging-Negative Strokes in Rat Models of Acute Internal Carotid Artery Occlusion Using Magnetic Resonance Spectroscopy
Brain damage in AICAO rats became evident at 2 h after successful modeling. MRS detected brain damage earlier than DWI, with Lac and Lip as the most sensitive markers, preceding changes in NAA, Cho, and ADC values.
Authors
- Zhengfei Yang (ORCID: https://orcid.org/0000-0001-9793-6910)
- Yuping Liu (ORCID: https://orcid.org/0000-0001-5539-5458)
- Haili Yang
- Zhihua Wu (ORCID: https://orcid.org/0000-0002-4213-1274)
- Xiaoling Li (ORCID: https://orcid.org/0000-0003-0338-2377)
- Siqi Liu (ORCID: https://orcid.org/0000-0001-9744-3681)
- Yanyu Zhang (ORCID: https://orcid.org/0000-0001-8992-1719)
- Zhifeng Liu (ORCID: https://orcid.org/0000-0001-5124-9824)
- Rongjian Jiang
- Haoyi Ye
Institutions
- Sun Yat-sen University (CN)
- Second Affiliated Hospital of Guangzhou Medical University (CN)
- Sun Yat-sen Memorial Hospital (CN)
- Guangzhou Medical University (CN)
Publication Details
- Journal
- Cerebrovascular Diseases
- Published
- 2025-06-28
- DOI
- https://doi.org/10.1159/000547134
- Primary Topic
- Neurological Disease Mechanisms and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00