Nativity, Race, Ethnicity, and Hypertensive Disorders During Pregnancy
<b>Background:</b> Previous research has examined the idea of the healthy immigrant effect and its potential application to pregnancy-related hypertensive disorders, particularly inracial and ethnic minority groups. The aim of this study is to examine how nativity, race, and ethnicity are related to prevalence of pregnancy-related hypertensive disorders. <b>Methods:</b> A retrospective cohort study was conducted using data from the PRAMS CDC dataset. These data were analyzed via <i>Χ</i><sup>2</sup> comparisons of prevalence of pregnancy-related hypertensive disorders in foreign and US-born mothers, including subgroup analyses for Black and Hispanic women. <b>Results</b>: A sample size of 63,648 was analyzed, and revealed significant differences in the prevalence of gestational hypertension between US-born vs. foreign-born Black mothers (12.6% vs. 8.0%, <i>Χ</i><sup>2</sup> (1, N = 12,046) = 36.92, <i>p</i> < 0.001), Hispanic mothers (9.5% vs. 7.2%, <i>Χ</i><sup>2</sup> (1, N = 11,524) = 18.236, <i>p</i> < 0.001), and the larger sample of mothers across all reported racial and ethnic backgrounds (11.0% vs. 7.0%, <i>Χ</i><sup>2</sup> (1, N = 63,648) = 163.835, <i>p</i> < 0.001). The results also revealed a significant difference in the prevalence of hypertension eclampsia between US-born and foreign-born Hispanic mothers (0.8% vs. 0.3%, <i>Χ</i><sup>2</sup> (1, N = 11,152) = 8.480, <i>p</i> = 0.004). <b>Conclusions:</b> The study results showed evidence of significantly lower prevalence of pregnancy-related hypertensive disorders among foreign-born mothers as compared to their US-born counterparts, both in the full study sample and specifically in the subsamples of women who self-identified as Black and women who self-identified as Hispanic. These variances by nativity, race, and ethnicity provide further insight into how the healthy immigrant effect can apply to pregnancy-related hypertensive disorders, particularly for women of racial and ethnic minorities.
Authors
- Madeline R. Fram (ORCID: https://orcid.org/0000-0002-1569-7707)
- Jeffrey M. Denney (ORCID: https://orcid.org/0000-0001-9131-5224)
- Kristen Quinn
Institutions
- Wake Forest University (US)
Publication Details
- Journal
- Journal of Clinical Medicine
- Published
- 2025-06-28
- DOI
- https://doi.org/10.3390/jcm14134594
- Primary Topic
- Pregnancy and preeclampsia studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Centers for Disease Control and Prevention