The reverse association between riboflavin intake and Helicobacter pylori infection in US adults: A cross-sectional study

These findings suggest that dietary riboflavin may inversely correlate with H. pylori infection in a dose-responsive manner, potentially mediated through mitochondrial function preservation, oxidative stress reduction, and gut microbiota modulation. While observational design precludes causal inference, the results underscore the need for prospective studies evaluating riboflavin's role in infection prevention.