Silent protocol modifications in multiple sclerosis clinical trials: a registry-based cross-sectional study
Silent protocol changes are common in MS clinical trials and potentially hinder the interpretation and applicability of results. Efforts must be made to promote more transparency in the field of MS clinical research.
Authors
- Marilina Puente-Hernandez (ORCID: https://orcid.org/0000-0002-1648-3102)
- Alejandro Rivero‐de‐Aguilar (ORCID: https://orcid.org/0000-0003-1818-8622)
- Alberto Ruano‐Raviña (ORCID: https://orcid.org/0000-0001-9927-7453)
- Joseph S. Ross (ORCID: https://orcid.org/0000-0002-9218-3320)
- Leonor Varela‐Lema (ORCID: https://orcid.org/0000-0001-8365-7961)
- Mónica Pérez‐Ríos (ORCID: https://orcid.org/0000-0003-4456-6631)
- Marta Mascareñas‐García (ORCID: https://orcid.org/0009-0006-8319-8922)
Institutions
- Yale New Haven Hospital (US)
- Universidade de Santiago de Compostela (ES)
- Yale University (US)
- Hospital Rio Carrion (ES)
- Instituto de Investigación Sanitaria de Santiago (ES)
- Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública (ES)
- Complejo Hospitalario de Pontevedra (ES)
Publication Details
- Journal
- Therapeutic Advances in Neurological Disorders
- Published
- 2025-06-30
- DOI
- https://doi.org/10.1177/17562864251335247
- Citations
- 1
- Primary Topic
- Statistical Methods in Clinical Trials
- Type
- article
- Field-Weighted Citation Impact
- 2.63