Alterations in Functional Connectivity and Network Topology During Remimazolam-Induced Unresponsiveness
Remimazolam induced reorganization of functional brain networks from highly connected, highly integrated complex networks to sparsely connected, locally modular cortical networks. These findings strengthen the notion that consciousness relies on networks capable of efficient information transmission that critically depends on the balance between global functional integration and segregation.
Authors
- Sijie Li (ORCID: https://orcid.org/0000-0002-8329-1186)
- Xin Wen (ORCID: https://orcid.org/0000-0003-2363-1190)
- Yiri Du (ORCID: https://orcid.org/0000-0002-8465-310X)
- Zhenhu Liang (ORCID: https://orcid.org/0000-0002-2467-9877)
- Changwei Wei (ORCID: https://orcid.org/0000-0001-5652-600X)
- Xuyang Wang (ORCID: https://orcid.org/0009-0001-6609-4463)
- Liang Bi
- Yi Sun (ORCID: https://orcid.org/0000-0002-6184-5782)
- Jing Wang (ORCID: https://orcid.org/0000-0002-3203-5131)
Institutions
- Capital Medical University (CN)
- Beijing Chao-Yang Hospital, Capital Medical University (CN)
- Yanshan University (CN)
- Inner Mongolia Medical University (CN)
Publication Details
- Journal
- Anesthesia & Analgesia
- Published
- 2025-06-30
- DOI
- https://doi.org/10.1213/ane.0000000000007614
- Citations
- 1
- Primary Topic
- Functional Brain Connectivity Studies
- Type
- article
- Field-Weighted Citation Impact
- 1.43