Stable Diffusion for Down Syndrome Face Generation

The growing need for diverse and inclusive datasets in computer vision has prompted research into synthetic image generation for underrepresented groups. This paper explores using Stable Diffusion XL (SD-XL 1.0-base) to generate highquality synthetic images of individuals with Down syndrome. By leveraging Low-Rank Adaptation (LoRA) and DreamBooth for concept-specific adjustments, our approach accurately reproduces key facial features. A curated dataset of 26 highresolution images was used to fine-tune the model. By training a CNN-based classification system using synthetic data, we demonstrate ResNet152V2 achieves 98.33% accuracy, underscoring the viability of synthetic images for data processing applications. The results enhance representation of individuals with Down syndrome in computer vision while addressing data scarcity and privacy concerns in biomedical imaging.

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Publication Details

Published
2025-05-14
DOI
https://doi.org/10.1109/biosmart66413.2025.11046078
Primary Topic
Generative Adversarial Networks and Image Synthesis
Type
article
Field-Weighted Citation Impact
0.00
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article

Stable Diffusion for Down Syndrome Face Generation

Hazem Zein, Muhammad Saeed, Amine Naït‐Ali
Generative Adversarial Networks and Image Synthesis
article

Stable Diffusion for Down Syndrome Face Generation

Hazem Zein, Muhammad Saeed, Amine Naït‐Ali
article en

Abstract

The growing need for diverse and inclusive datasets in computer vision has prompted research into synthetic image generation for underrepresented groups. This paper explores using Stable Diffusion XL (SD-XL 1.0-base) to generate highquality synthetic images of individuals with Down syndrome. By leveraging Low-Rank Adaptation (LoRA) and DreamBooth for concept-specific adjustments, our approach accurately reproduces key facial features. A curated dataset of 26 highresolution images was used to fine-tune the model. By training a CNN-based classification system using synthetic data, we demonstrate ResNet152V2 achieves 98.33% accuracy, underscoring the viability of synthetic images for data processing applications. The results enhance representation of individuals with Down syndrome in computer vision while addressing data scarcity and privacy concerns in biomedical imaging.

Paris-Est Sup (FR)
Gender equality
Openalex Percentile: Top 86%
Generative Adversarial Networks and Image Synthesis
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