Features of socialandbiological status and clinicalandlaboratory information for pregnant with the high degree of infectious risk

The objective: to learn the features of social-and-biological status and clinical-and-laboratory information for pregnant with the high degree of infectious risk.Materials and methods.100 women appeared a research object on the term of 38–40 week with the high degree of infectious risk.Plugging criteria in this group were: a consent of woman is to the conduct of research; clinical-and-anamnestic information (gestational pyelonephritis or d’exacerbation of chronic pyelonephritis during pregnancy, threat of terminating pregnancy during all term of gestation, presence in anamnesis of heterospecific inflammatory diseases of female reproductive organs, post-natal and post-abortion endometritis); a singleton pregnancy is on the term of 38–40 week; clinical, bacteriological and backterioscopies of sign of inflammatory process (presence of colpitis, confirmed by information of research of backterioscopy, identification conditionally pathogenic microorganisms in a cervical canal in an amount more than 103–4 CFU/ml from data of bacteriological research); signs of the intrauterine infecting are from data of echographic research: placentomegaly, presence of suspension in amniotic fluid, ventriculomegaly and pyeloectasia in fetus.The criteria of exception from a group were: term of pregnancy loss than 37 weeks, including premature outflow of amniotic fluid at prematurely; presence of heavy obstetric and extragenital pathology (heavy preeclampsia, diabetes mellitus, including gestational, respiratory and cardiac insufficiency and others like that); persons are with a polyvalent allergic reaction on medicinal preparations; patients, which gave up research which was conducted.To the complex of the conducted researches clinical, laboratory instrumental, microbiological and statistical methods were included. Results. The analysis of features of extragenital pathology rotined for the patients of both groups, that reliable differences in frequency of diseases of broncho-pulmonary, cardio-vascular, endocrine system and diseases of digestive tract and urinoexcretory ways also did not have been observed. However more high frequency of inflammatory diseases of ENT organs, despite expectations, was in 2 groups (34,4±3,4% against 14,3±1,4% for patients from endometritis) (p < 0,05). For patients 2 groups the reliable more frequent was found out myopia (18,8±1,8% against 4,0±0,7% in a 1 group) (p < 0,05). For patients with developed post-natal endometritis duratio. Perinatology and reproductology:from research to practice of operation was for certain higher than for women with a non-compliance puerperium (77,1±4,2 hours against 52,2±3,6 hour respectively) (p < 0,05). For the women of a 1 group higher intraoperative blood loss (533,3±21,8 ml) was also marked for certain as compared to 2 (430,6±8,2 ml) (p<0,05). It allows to examine afore-mentioned factors as prognostically unfavorable for development of post-natal endometritis.Conclusions. Basic clinical-and-anamnestic features for patients with post-natal endometritis were threat of termination pregnancy of early terms, which can be the marker of presence of infection in the cavities of uterus, and also lower weight of patients, which can be related to the higher antigen loading on the kilogram of weight of patient. Births for patients with post-natal endometritis were characterized by more protracted motion of the III period, in the case of operative delivery – by the increase of time of operation on the average on 20 minutes, and also greater blood loss. From laboratory indexes most informing were leukocytosis with the change of leukocyte formula to the left and increase of erythrocyte sedimentation rate, from data of echographic research of uterus – increase of anterior-posterior size.

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Publication Details

Journal
Perinatology and reproductology from research to practice
Published
2025-01-01
DOI
https://doi.org/10.52705/2788-6190-2025-01.2-01
Primary Topic
Human Health and Disease
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article
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article

Features of socialandbiological status and clinicalandlaboratory information for pregnant with the high degree of infectious risk

Andrey Prishchepa
Perinatology and reproductology from research to practice
Human Health and Disease
article

Features of socialandbiological status and clinicalandlaboratory information for pregnant with the high degree of infectious risk

Andrey Prishchepa
article en

Abstract

The objective: to learn the features of social-and-biological status and clinical-and-laboratory information for pregnant with the high degree of infectious risk.Materials and methods.100 women appeared a research object on the term of 38–40 week with the high degree of infectious risk.Plugging criteria in this group were: a consent of woman is to the conduct of research; clinical-and-anamnestic information (gestational pyelonephritis or d’exacerbation of chronic pyelonephritis during pregnancy, threat of terminating pregnancy during all term of gestation, presence in anamnesis of heterospecific inflammatory diseases of female reproductive organs, post-natal and post-abortion endometritis); a singleton pregnancy is on the term of 38–40 week; clinical, bacteriological and backterioscopies of sign of inflammatory process (presence of colpitis, confirmed by information of research of backterioscopy, identification conditionally pathogenic microorganisms in a cervical canal in an amount more than 103–4 CFU/ml from data of bacteriological research); signs of the intrauterine infecting are from data of echographic research: placentomegaly, presence of suspension in amniotic fluid, ventriculomegaly and pyeloectasia in fetus.The criteria of exception from a group were: term of pregnancy loss than 37 weeks, including premature outflow of amniotic fluid at prematurely; presence of heavy obstetric and extragenital pathology (heavy preeclampsia, diabetes mellitus, including gestational, respiratory and cardiac insufficiency and others like that); persons are with a polyvalent allergic reaction on medicinal preparations; patients, which gave up research which was conducted.To the complex of the conducted researches clinical, laboratory instrumental, microbiological and statistical methods were included. Results. The analysis of features of extragenital pathology rotined for the patients of both groups, that reliable differences in frequency of diseases of broncho-pulmonary, cardio-vascular, endocrine system and diseases of digestive tract and urinoexcretory ways also did not have been observed. However more high frequency of inflammatory diseases of ENT organs, despite expectations, was in 2 groups (34,4±3,4% against 14,3±1,4% for patients from endometritis) (p < 0,05). For patients 2 groups the reliable more frequent was found out myopia (18,8±1,8% against 4,0±0,7% in a 1 group) (p < 0,05). For patients with developed post-natal endometritis duratio. Perinatology and reproductology:from research to practice of operation was for certain higher than for women with a non-compliance puerperium (77,1±4,2 hours against 52,2±3,6 hour respectively) (p < 0,05). For the women of a 1 group higher intraoperative blood loss (533,3±21,8 ml) was also marked for certain as compared to 2 (430,6±8,2 ml) (p<0,05). It allows to examine afore-mentioned factors as prognostically unfavorable for development of post-natal endometritis.Conclusions. Basic clinical-and-anamnestic features for patients with post-natal endometritis were threat of termination pregnancy of early terms, which can be the marker of presence of infection in the cavities of uterus, and also lower weight of patients, which can be related to the higher antigen loading on the kilogram of weight of patient. Births for patients with post-natal endometritis were characterized by more protracted motion of the III period, in the case of operative delivery – by the increase of time of operation on the average on 20 minutes, and also greater blood loss. From laboratory indexes most informing were leukocytosis with the change of leukocyte formula to the left and increase of erythrocyte sedimentation rate, from data of echographic research of uterus – increase of anterior-posterior size.

Perinatology and reproductology from research to practiceVol. 5(1-2)
Openalex Percentile: Top 78%
Human Health and Disease
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