Candidemia and antifungal susceptibility in Peruvian hospitals

Worldwide, Candida bloodstream infections have presented an increase in non-albicans Candida species and resistance to antifungal agents. Objective: To describe the microbiological characteristics of consecutive Candida blood culture isolates. Methods: This study analyzed 73 consecutive Candida blood isolates recovered between July 2017 and July 2019 from routine patient care at 15 Peruvian hospitals, assessing susceptibility to four antifungal agents. Results: The species most frequently detected were Candida parapsilosis 39 (53.4%), Candida albicans 23 (31.5%), and Candida tropicalis 5 (6.8%). Conclusions: All isolates were susceptible to amphotericin B, fluconazole, voriconazole, and anidulafungin. There is a predominance of non-albicans Candida cases in Peru and a high susceptibility to current antifungal drugs.

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Journal
Revista Médica Herediana
Published
2025-06-30
DOI
https://doi.org/10.20453/rmh.v36i2.6233
Primary Topic
Antifungal resistance and susceptibility
Type
article
Field-Weighted Citation Impact
0.00

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article

Candidemia and antifungal susceptibility in Peruvian hospitals

Jan Jacobs, Michelle Regal Ludowieg, Fernando Escalante, Beatriz Bustamante et al.
Revista Médica Herediana
Antifungal resistance and susceptibility
article

Candidemia and antifungal susceptibility in Peruvian hospitals

Jan Jacobs, Michelle Regal Ludowieg, Fernando Escalante, Beatriz Bustamante, Fiorella Krapp, Coralith García, Romina Rios-Blanco, Marcello Olsen-Verme
article en

Abstract

Worldwide, Candida bloodstream infections have presented an increase in non-albicans Candida species and resistance to antifungal agents. Objective: To describe the microbiological characteristics of consecutive Candida blood culture isolates. Methods: This study analyzed 73 consecutive Candida blood isolates recovered between July 2017 and July 2019 from routine patient care at 15 Peruvian hospitals, assessing susceptibility to four antifungal agents. Results: The species most frequently detected were Candida parapsilosis 39 (53.4%), Candida albicans 23 (31.5%), and Candida tropicalis 5 (6.8%). Conclusions: All isolates were susceptible to amphotericin B, fluconazole, voriconazole, and anidulafungin. There is a predominance of non-albicans Candida cases in Peru and a high susceptibility to current antifungal drugs.

Revista Médica HeredianaVol. 36(2)
Universidad Peruana Cayetano Heredia (PE), Instituut voor Tropische Geneeskunde (BE)
Alexander von Humboldt-Stiftung, Instituut voor Tropische Geneeskunde
Openalex Percentile: Top 81%
Antifungal resistance and susceptibility
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