Candidemia and antifungal susceptibility in Peruvian hospitals
Worldwide, Candida bloodstream infections have presented an increase in non-albicans Candida species and resistance to antifungal agents. Objective: To describe the microbiological characteristics of consecutive Candida blood culture isolates. Methods: This study analyzed 73 consecutive Candida blood isolates recovered between July 2017 and July 2019 from routine patient care at 15 Peruvian hospitals, assessing susceptibility to four antifungal agents. Results: The species most frequently detected were Candida parapsilosis 39 (53.4%), Candida albicans 23 (31.5%), and Candida tropicalis 5 (6.8%). Conclusions: All isolates were susceptible to amphotericin B, fluconazole, voriconazole, and anidulafungin. There is a predominance of non-albicans Candida cases in Peru and a high susceptibility to current antifungal drugs.
Authors
- Jan Jacobs (ORCID: https://orcid.org/0000-0002-8657-6777)
- Michelle Regal Ludowieg (ORCID: https://orcid.org/0000-0002-0751-5328)
- Fernando Escalante (ORCID: https://orcid.org/0000-0003-4501-9066)
- Beatriz Bustamante (ORCID: https://orcid.org/0000-0002-6826-5211)
- Fiorella Krapp (ORCID: https://orcid.org/0000-0002-8404-2827)
- Coralith García (ORCID: https://orcid.org/0000-0002-7933-1843)
- Romina Rios-Blanco (ORCID: https://orcid.org/0000-0003-2149-4540)
- Marcello Olsen-Verme (ORCID: https://orcid.org/0000-0002-0007-2050)
Institutions
- Universidad Peruana Cayetano Heredia (PE)
- Instituut voor Tropische Geneeskunde (BE)
Publication Details
- Journal
- Revista Médica Herediana
- Published
- 2025-06-30
- DOI
- https://doi.org/10.20453/rmh.v36i2.6233
- Primary Topic
- Antifungal resistance and susceptibility
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Alexander von Humboldt-Stiftung
- Instituut voor Tropische Geneeskunde