A Case of Elbow Extension Limitation Caused by Phlebosclerosis Following Peripheral Intravenous Chemotherapy: A Case Report and Literature Review

We report a rare case of phlebosclerosis in the left antecubital region after peripheral intravenous chemotherapy, which caused elbow contracture. A 54-year-old woman with breast cancer underwent partial mastectomy of the right breast and 8 courses of neoadjuvant chemotherapy, 6 of which were administered via venipuncture in the left forearm. She developed progressive flexion contracture of the left elbow despite rehabilitation. Two cord-like fibrotic veins were identified in the antecubital region and surgically excised. Postoperative rehabilitation led to full elbow extension within 5 months. In cases with elbow extension limitation, proactive surgical intervention should be considered.

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Publication Details

Journal
Annals of Vascular Diseases
Published
2025-01-01
DOI
https://doi.org/10.3400/avd.cr.25-00055
Primary Topic
Chemotherapy-related skin toxicity
Type
article
Field-Weighted Citation Impact
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article

A Case of Elbow Extension Limitation Caused by Phlebosclerosis Following Peripheral Intravenous Chemotherapy: A Case Report and Literature Review

Kazunori Inuzuka, Naoki Unno, Masaki Sano, Hajime Tsuyuki et al.
Annals of Vascular Diseases
Chemotherapy-related skin toxicity
article

A Case of Elbow Extension Limitation Caused by Phlebosclerosis Following Peripheral Intravenous Chemotherapy: A Case Report and Literature Review

Kazunori Inuzuka, Naoki Unno, Masaki Sano, Hajime Tsuyuki, Hiroya Takeuchi, Nozomu Ishikawa, Kazuto Katahashi, Yusuke Endo
article en

Abstract

We report a rare case of phlebosclerosis in the left antecubital region after peripheral intravenous chemotherapy, which caused elbow contracture. A 54-year-old woman with breast cancer underwent partial mastectomy of the right breast and 8 courses of neoadjuvant chemotherapy, 6 of which were administered via venipuncture in the left forearm. She developed progressive flexion contracture of the left elbow despite rehabilitation. Two cord-like fibrotic veins were identified in the antecubital region and surgically excised. Postoperative rehabilitation led to full elbow extension within 5 months. In cases with elbow extension limitation, proactive surgical intervention should be considered.

Annals of Vascular DiseasesVol. 18(1)
Hamamatsu University School of Medicine (JP), Hamamatsu Medical Center (JP)
Zero hunger
Openalex Percentile: Top 72%
Chemotherapy-related skin toxicity
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A Case of Elbow Extension Limitation Caused by Phlebosclerosis Following Peripheral Intravenous Chemotherapy: A Case Report and Literature Review — Kazunori Inuzuka, Naoki Unno, et al. · Annals of Vascular Diseases (2025) | TGRS Research Map | TGRS