Solid-state nanopore detection of metal ions <i>via</i> a DNAzyme–Catalytic Hairpin Assembly reaction
Based on the indirect transduction strategy (ITS), we utilize a DNAzyme-CHA reaction to transduce lead(II), which cannot be directly detected by a glass nanopore, into controllable CHA products. This enables the accurate recognition of lead(II). The signal amplification method significantly enhances the resolution of glass nanopores and is expected to broaden their application scope.
Authors
- Yan Zhao (ORCID: https://orcid.org/0000-0002-4680-0500)
- Yesheng Wang (ORCID: https://orcid.org/0000-0003-3923-1028)
- Ruiping Wu
- Jin Yu (ORCID: https://orcid.org/0000-0003-1074-2465)
- Chunmiao Yu
- Bingling Li (ORCID: https://orcid.org/0000-0002-7224-0041)
- Jinbo Zhu (ORCID: https://orcid.org/0000-0003-4935-825X)
- Lu Zhou
- Yanru Li (ORCID: https://orcid.org/0000-0002-7052-1165)
- Tianlu Wang (ORCID: https://orcid.org/0000-0001-9972-7821)
- Lan Shao
Institutions
- University of Science and Technology of China (CN)
- Chinese Academy of Sciences (CN)
- Dalian University of Technology (CN)
- Changchun Institute of Applied Chemistry (CN)
- Dalian University (CN)
- Xi'an Medical University (CN)
- Liaoning Cancer Hospital & Institute (CN)
Publication Details
- Journal
- Chemical Communications
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1039/d5cc03429a
- Primary Topic
- Nanopore and Nanochannel Transport Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Dalian University of Technology
- Department of Science and Technology of Liaoning Province