A Hepatoblastoma in Four-Year-Old: Diagnosis and Chemotherapy Treatment

Introduction: Hepatoblastoma is a primary liver malignancy that often occurs in children under 5 years of age. According to the Surveillance, Epidemiology, and End Results (SEER) database, the incidence of liver tumors in children is estimated to be 0.47 (0.24–0.65)/1,000,000/year. The International Society of Pediatric Oncology Liver Tumor Study states that childhood liver cancer may be sensitive to chemotherapy. Chemotherapy strategies rely on cisplatin, as it remains the most active single agent against hepatoblastoma. In this study, we aim to discover of diagnosis and outcome of hepatoblastoma patients treated with cisplatin chemotherapy. Case Presentation: This case reports a pediatric patient aged 4 years 3 months 13 days with complaints of an enlarged stomach. The results of physical examination, laboratory, radiology, and anatomical pathology results showed the presence of hepatoblastoma. The patient is currently undergoing cisplatin chemotherapy. Diagnosis of hepatoblastoma is based on clinical features, increased serum AFP levels, radiological images, and anatomical pathology. The International Society of Pediatric Oncology Liver Tumor Study states that childhood liver cancer may be sensitive to chemotherapy. Chemotherapy strategies rely on cisplatin, as it remains the most active single agent against hepatoblastoma.Conclusion: This study discusses the diagnosis and response to chemotherapy in hepatoblastoma patients. Given the limited data in this case, it is recommended to carry out further research regarding the side effects of chemotherapy for hepatoblastoma.