Electrochemical hydrotrifluoromethylation of alkynes
We report the electrochemical hydrotrifluoromethylation of alkynes using the Langlois reagent as a CF<sub>3</sub> source. The mild conditions enable broad functional group tolerance and allow late-stage functionalization. Mechanistic studies reveal that DMSO serves a dual role as both solvent and hydrogen atom donor.
Authors
- Eun Jin Cho (ORCID: https://orcid.org/0000-0002-6607-1851)
- Jihoon Jang (ORCID: https://orcid.org/0000-0001-5272-2441)
Institutions
- Chung-Ang University (KR)
Publication Details
- Journal
- Chemical Communications
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1039/d5cc02370j
- Citations
- 2
- Primary Topic
- Fluorine in Organic Chemistry
- Type
- article
- Field-Weighted Citation Impact
- 1.58