Efficacy and safety of Angio-Seal™ VIP vascular closure device compared to manual compression for access site hemostasis in patients who underwent antegrade common femoral artery puncture for popliteal and/or below the knee intervention

Aim: Antegrade common femoral artery puncture has become the preferred method for popliteal and below-the-knee interventions. There has been an increasing use of vascular closure devices aimed at reducing hospital stays and enhancing patient comfort. This study aimed to evaluate the efficacy and safety of the Angio-Seal™ VIP vascular closure device compared to manual compression for access site sealing in patients with popliteal and/or below-the-knee disease who underwent antegrade common femoral artery puncture. Material and Methods: A total of 104 patients who underwent revascularization through antegrade common femoral artery puncture were randomly assigned to two groups based on the technique used for access site sealing: Angio-Seal™ VIP (n = 52) and manual compression (n = 52). The effectiveness of the two methods and the duration of hospitalization for both groups were analyzed. Complication rates were assessed during hospitalization and at a 3-month follow-up. Results: Successful access site hemostasis without complications was achieved in 48 of 52 patients (92.30%) in the Angio-Seal™ VIP group and in 47 of 52 patients (90.38%) in the manual compression group (p = 0.42). Major complication rates did not differ between the Angio-Seal™ VIP (3.84%) and manual compression groups (3.84%, p = 1.00). However, the duration of hospitalization was significantly shorter in the Angio-Seal™ VIP group (10.4 hours vs. 28.6 hours, p = 0.03). Conclusions: The Angio-Seal™ VIP device demonstrated safety and effectiveness comparable to manual compression for achieving hemostasis at the access site in patients undergoing antegrade common femoral artery puncture and was associated with a shorter duration of hospitalization.