Management of Chronic Respiratory Diseases: A Retrospective Analysis of Demographic Predictors and Treatment Outcomes in Asthma and Chronic Obstructive Pulmonary Disease

Context: Chronic respiratory conditions such as asthma and COPD represent significant global health challenges. This study aims to elucidate the interplay between demographic characteristics, disease prevalence, and treatment outcomes by examining a cohort of 203 patients with these disorders. Aims: The study analyses demographic profiles, disease prevalence, and treatment outcomes among individuals with asthma and COPD. It also investigates relationships among exacerbation rates, comorbidities, and healthcare utilization. Subjects and Methods: A retrospective analysis focused on patient demographics, smoking habits, comorbidities, medication use, exacerbation frequency, and healthcare utilization. Statistical Analysis Used: Prevalence, outcomes, and management trends were assessed using Microsoft Excel and SPSS (v22). Descriptive statistics (mean, SD, frequency) were calculated. Chi-square tests were used for categorical variables; t-tests for continuous variables. P <0.05 was considered statistically significant. Results: The cohort mainly comprised older adults, with 60.1% female and 37.4% aged 61–80. Most (92.6%) were Saudi nationals. Only 12.8% were current smokers; 76.4% had unclear smoking histories. Asthma was more prevalent (63.1%) than COPD (29.1%); 7.9% had both. Most patients used inhaled corticosteroids (99%) and long-acting β-agonists (95.1%). ICU admissions occurred in 38.4%, with 45.8% experiencing exacerbations. Pneumonia was undiagnosed in 56.7%. Among COVID-19 patients, 5.4% had exacerbations. The overall mortality rate was 7.9%. Conclusions: Statistically significant associations between disease type, age, healthcare utilization, and ICU admissions highlight the need for stratified management. Incorporating validated predictors may improve prognosis and reduce mortality.

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Publication Details

Journal
Journal of Nature and Science of Medicine
Published
2025-04-01
DOI
https://doi.org/10.4103/jnsm.jnsm_164_24
Primary Topic
Chronic Obstructive Pulmonary Disease (COPD) Research
Type
article
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article

Management of Chronic Respiratory Diseases: A Retrospective Analysis of Demographic Predictors and Treatment Outcomes in Asthma and Chronic Obstructive Pulmonary Disease

Saeed Saleh Aziz Alghamdi, Raed Alharbi, Saba Beigh, Ali Alghamdi et al.
1 links
Journal of Nature and Science of Medicine
Chronic Obstructive Pulmonary Disease (COPD) Research
article

Management of Chronic Respiratory Diseases: A Retrospective Analysis of Demographic Predictors and Treatment Outcomes in Asthma and Chronic Obstructive Pulmonary Disease

Saeed Saleh Aziz Alghamdi, Raed Alharbi, Saba Beigh, Ali Alghamdi, Saleh Alzahrani, Mohammed Al-Shehri, Mohammed Alghamdi, Rabab Morsy Ahmad
article en

Abstract

Context: Chronic respiratory conditions such as asthma and COPD represent significant global health challenges. This study aims to elucidate the interplay between demographic characteristics, disease prevalence, and treatment outcomes by examining a cohort of 203 patients with these disorders. Aims: The study analyses demographic profiles, disease prevalence, and treatment outcomes among individuals with asthma and COPD. It also investigates relationships among exacerbation rates, comorbidities, and healthcare utilization. Subjects and Methods: A retrospective analysis focused on patient demographics, smoking habits, comorbidities, medication use, exacerbation frequency, and healthcare utilization. Statistical Analysis Used: Prevalence, outcomes, and management trends were assessed using Microsoft Excel and SPSS (v22). Descriptive statistics (mean, SD, frequency) were calculated. Chi-square tests were used for categorical variables; t-tests for continuous variables. P <0.05 was considered statistically significant. Results: The cohort mainly comprised older adults, with 60.1% female and 37.4% aged 61–80. Most (92.6%) were Saudi nationals. Only 12.8% were current smokers; 76.4% had unclear smoking histories. Asthma was more prevalent (63.1%) than COPD (29.1%); 7.9% had both. Most patients used inhaled corticosteroids (99%) and long-acting β-agonists (95.1%). ICU admissions occurred in 38.4%, with 45.8% experiencing exacerbations. Pneumonia was undiagnosed in 56.7%. Among COVID-19 patients, 5.4% had exacerbations. The overall mortality rate was 7.9%. Conclusions: Statistically significant associations between disease type, age, healthcare utilization, and ICU admissions highlight the need for stratified management. Incorporating validated predictors may improve prognosis and reduce mortality.

Journal of Nature and Science of MedicineVol. 8(2)
King Fahad Hospital Jeddah (SA), Al Baha University (SA)
Openalex Percentile: Top 75%
Chronic Obstructive Pulmonary Disease (COPD) Research
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