A comprehensive update on the cost-effectiveness of 10-year denosumab vs alendronate in postmenopausal women with osteoporosis in the United States

Ten-year denosumab treatment would be cost-effective compared with 5 years of alendronate, followed by a 2-year drug holiday and 3 years of alendronate at the threshold of $150,000. Cost-effectiveness was demonstrated across most scenarios with robust PSA results.

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Publication Details

Journal
Archives of Osteoporosis
Published
2025-06-30
DOI
https://doi.org/10.1007/s11657-025-01564-x
Primary Topic
Bone health and osteoporosis research
Type
article
Field-Weighted Citation Impact
0.00

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article

A comprehensive update on the cost-effectiveness of 10-year denosumab vs alendronate in postmenopausal women with osteoporosis in the United States

Eric J. Yeh, Jack Badaracco, Matia Saeedian
1 links
Archives of Osteoporosis
Bone health and osteoporosis research
article

A comprehensive update on the cost-effectiveness of 10-year denosumab vs alendronate in postmenopausal women with osteoporosis in the United States

Eric J. Yeh, Jack Badaracco, Matia Saeedian
article en

Abstract

Ten-year denosumab treatment would be cost-effective compared with 5 years of alendronate, followed by a 2-year drug holiday and 3 years of alendronate at the threshold of $150,000. Cost-effectiveness was demonstrated across most scenarios with robust PSA results.

Archives of OsteoporosisVol. 20(1)
Amgen (United States) (US)
Amgen
Good health and well-being
Openalex Percentile: Top 80%
Bone health and osteoporosis research
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