A case of vitiligo secondary to discoid lupus erythematosus treated with tofacitinib

This case illustrates the successful use of tofacitinib in treating vitiligo secondary to DLE, emphasizing the therapeutic potential of JAK inhibition in overlapping autoimmune skin conditions. Further studies are warranted to validate its long-term safety and efficacy in such complex cases. This is a single case report with a short follow-up duration. Lack of immunologic profiling limits broader generalizability. Controlled studies are needed to confirm these findings.

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Publication Details

Journal
Medicine
Published
2025-06-27
DOI
https://doi.org/10.1097/md.0000000000043118
Primary Topic
melanin and skin pigmentation
Type
article
Field-Weighted Citation Impact
0.00
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article

A case of vitiligo secondary to discoid lupus erythematosus treated with tofacitinib

Ping Wang, Shiwen Wang, Chenyu Tang, Sha Jin et al.
Medicine
melanin and skin pigmentation
article

A case of vitiligo secondary to discoid lupus erythematosus treated with tofacitinib

Ping Wang, Shiwen Wang, Chenyu Tang, Sha Jin, Shiyu Jin
article en

Abstract

This case illustrates the successful use of tofacitinib in treating vitiligo secondary to DLE, emphasizing the therapeutic potential of JAK inhibition in overlapping autoimmune skin conditions. Further studies are warranted to validate its long-term safety and efficacy in such complex cases. This is a single case report with a short follow-up duration. Lack of immunologic profiling limits broader generalizability. Controlled studies are needed to confirm these findings.

MedicineVol. 104(26)
Zhejiang Chinese Medical University (CN), Third People's Hospital of Hangzhou (CN), The Third Affiliated Hospital of Zhejiang Chinese Medical University (CN)
Good health and well-being
Openalex Percentile: Top 84%
melanin and skin pigmentation
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A case of vitiligo secondary to discoid lupus erythematosus treated with tofacitinib — Ping Wang, Shiwen Wang, et al. · Medicine (2025) | TGRS Research Map | TGRS