Relationship between hydroxychloroquine blood levels and lupus activity through the lens of the type 1 and type 2 lupus model: a cross-sectional study
Low HCQ levels are associated with increased type 1 and type 2 SLE activities, particularly for the <i>mixed activity</i> group, suggesting that immunologic activity may contribute to type 2 symptoms in some patients.
Authors
- Mithu Maheswaranathan (ORCID: https://orcid.org/0000-0003-0866-0022)
- Stephen J. Balevic (ORCID: https://orcid.org/0000-0002-4016-1680)
- Amanda M. Eudy (ORCID: https://orcid.org/0000-0002-3107-5545)
- Jennifer L Rogers (ORCID: https://orcid.org/0000-0001-5524-8642)
- Jayanth Doss (ORCID: https://orcid.org/0000-0002-7326-7107)
- Roberta Vezza Alexander (ORCID: https://orcid.org/0000-0001-8827-8637)
- Lisa Criscione‐Schreiber (ORCID: https://orcid.org/0000-0003-3287-9251)
- Tyler O’Malley (ORCID: https://orcid.org/0000-0002-4439-1395)
- Rebecca E. Sadun (ORCID: https://orcid.org/0000-0001-7768-3565)
- Megan E. B. Clowse (ORCID: https://orcid.org/0000-0002-8579-3470)
- Kai Sun (ORCID: https://orcid.org/0000-0002-8406-2932)
Institutions
- Duke University (US)
- Clinical Research Institute (US)
- Duke Medical Center (US)
Publication Details
- Journal
- Lupus Science & Medicine
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1136/lupus-2025-001531
- Citations
- 1
- Primary Topic
- Systemic Lupus Erythematosus Research
- Type
- article
- Field-Weighted Citation Impact
- 1.67
Funders
- National Center for Advancing Translational Sciences
- National Institute on Minority Health and Health Disparities