The relationship between osteopenia and vascular tone disorders in mature and elderly women

Objective. To investigate some indicators of vascular tone in women over 45 years of age with and without osteopenia for the prevention of osteoporosis. Material and methods. 153 patients were examined, divided into 2 groups according to age: 1st (n=83) – 45–59 years old; 2nd (n=70) – 60–74 years old. Ultrasound densitometry of the calcaneal bone was performed using a FURUNO CM-200 light densitometer (Japan) with determination of the ultrasound transmission rate (SOS m/s), T-criterion. Pulse wave analysis (Multiscan BC-OXi (Russia)) was used to study microcirculation (stiffness of large arteries (SI), tone of medium and small arteries (RI), peripheral vascular resistance (PSS)). Results. The prevalence of osteopenia in the study sample in the outpatient setting ranged from 19.2% to 38.5% between the ages of 45 and 74 years. Evaluation of microcirculation indicators in mature women depending on the presence or absence of osteopenia showed that people with osteopenia had higher PSS, SI, RI numbers. In women over 60 years of age changes in vascular stiffness and microcirculation parameters were more strongly associated with age rather than the presence of osteopenia. Conclusions. In adulthood, women stand out as a risk group associated with the presence of osteopenia, changes in vascular stiffness and microcirculation, which requires a personalized approach to prevention. In old age, 95% of cases have increased vascular stiffness, changes in microcirculation in combination with osteopenia, which suggests active dynamic observation and treatment of concomitant cardiovascular disease