Extensive T‐Wave Inversion Associated With Chest Pain: Elucidating the Underlying Truth

A patient with episodic chest pain, diaphoresis, amaurosis, and dizziness, along with a history of hypertension, presented with electrocardiographic findings of ST elevation in aVR, diffuse T-wave inversion, and QTc prolongation. Initial diagnosis of NSTEMI was reconsidered after coronary angiography excluded significant stenosis, revealing myocardial bridging. Echocardiography and cardiac MRI showed preserved function without ischemia. Markedly elevated plasma renin and urinary normetanephrine, along with a retroperitoneal mass, suggested paraganglioma. Laparoscopic resection confirmed a 4.0 × 3.5 cm paraganglioma. This case highlights the importance of recognizing atypical ECG patterns that may mimic ischemia in catecholamine-secreting tumors to guide timely diagnosis and intervention.

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Publication Details

Journal
Annals of Noninvasive Electrocardiology
Published
2025-06-30
DOI
https://doi.org/10.1111/anec.70102
Citations
1
Primary Topic
Takotsubo Cardiomyopathy and Associated Phenomena
Type
article
Field-Weighted Citation Impact
1.39

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article

Extensive T‐Wave Inversion Associated With Chest Pain: Elucidating the Underlying Truth

Xinxin Di, Jing‐Xiu Li, Min Gao, Xue‐Qi Li
1 citations
Annals of Noninvasive Electrocardiology
Takotsubo Cardiomyopathy and Associated Phenomena
1.39
article

Extensive T‐Wave Inversion Associated With Chest Pain: Elucidating the Underlying Truth

Xinxin Di, Jing‐Xiu Li, Min Gao, Xue‐Qi Li
article en
1 citations

Abstract

A patient with episodic chest pain, diaphoresis, amaurosis, and dizziness, along with a history of hypertension, presented with electrocardiographic findings of ST elevation in aVR, diffuse T-wave inversion, and QTc prolongation. Initial diagnosis of NSTEMI was reconsidered after coronary angiography excluded significant stenosis, revealing myocardial bridging. Echocardiography and cardiac MRI showed preserved function without ischemia. Markedly elevated plasma renin and urinary normetanephrine, along with a retroperitoneal mass, suggested paraganglioma. Laparoscopic resection confirmed a 4.0 × 3.5 cm paraganglioma. This case highlights the importance of recognizing atypical ECG patterns that may mimic ischemia in catecholamine-secreting tumors to guide timely diagnosis and intervention.

Annals of Noninvasive ElectrocardiologyVol. 30(4)
University of Science and Technology of China (CN), Harbin Medical University (CN), Fourth Affiliated Hospital of Harbin Medical University (CN)
Aerospace Center Hospital
Good health and well-being
Openalex Percentile: Top 18%
Takotsubo Cardiomyopathy and Associated Phenomena
1.39
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