Hepatoprotective Activity of Red Ginger Extract on Acetaminophen-induced Liver Injury Models in HepG2 Cells

These results indicate that RGE exerts hepatoprotective effects through increased IL-10 production, alongside the suppression of NO, IL-1β, IL-6, as well as Casp-3, Casp-9, and JNK gene expression.

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Publication Details

Journal
Annals of African Medicine
Published
2025-06-30
DOI
https://doi.org/10.4103/aam.aam_91_24
Primary Topic
Drug-Induced Hepatotoxicity and Protection
Type
article
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article

Hepatoprotective Activity of Red Ginger Extract on Acetaminophen-induced Liver Injury Models in HepG2 Cells

Diah Kartika Pratamı, Philips Onggowidjaja, Hanna Sari Widya Kusuma, Nindia Salsabila Mia Dewi et al.
Annals of African Medicine
Drug-Induced Hepatotoxicity and Protection
article

Hepatoprotective Activity of Red Ginger Extract on Acetaminophen-induced Liver Injury Models in HepG2 Cells

Diah Kartika Pratamı, Philips Onggowidjaja, Hanna Sari Widya Kusuma, Nindia Salsabila Mia Dewi, Dian Ratih Laksmıtawatı, Rizal Azis, Didik Priyandoko, Rita Tjokropranoto, Deni Rahmat, Wahyu Surakusumah, Dhanar Septyawan Hadiprasetyo, Wahyu Widowati
article en

Abstract

These results indicate that RGE exerts hepatoprotective effects through increased IL-10 production, alongside the suppression of NO, IL-1β, IL-6, as well as Casp-3, Casp-9, and JNK gene expression.

Annals of African MedicineVol. 24(4)
Indonesia University of Education (ID), Maranatha Christian University (ID), University of Indonesia (ID), Pancasila University (ID), Universitas Jenderal Achmad Yani (ID)
Good health and well-being
Openalex Percentile: Top 80%
Drug-Induced Hepatotoxicity and Protection
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Hepatoprotective Activity of Red Ginger Extract on Acetaminophen-induced Liver Injury Models in HepG2 Cells — Diah Kartika Pratamı, Philips Onggowidjaja, et al. · Annals of African Medicine (2025) | TGRS Research Map | TGRS