The Study of Novel Sepsis Biomarkers Presepsin, Interleukin-27, Hepcidin, Plasma Chitotriosidase in Intensive Care Unit Patients with Sepsis and Correlation with Serum Procalcitonin Levels

This study supports the potential of presepsin and hepcidin as novel biomarkers for sepsis in ICU patients. These markers showed strong correlations with PCT and high rates of abnormal levels in sepsis patients. IL-27 and chitotriosidase showed less promise in our study population. Integrating these novel biomarkers, particularly presepsin and hepcidin, into clinical practice could potentially improve early diagnosis and management of sepsis in critical care settings.