Study Limitations in Statin Use and Risk of Hepatocellular Carcinoma

To the Editor I read with interest the study of Choi et al1 showing that statin use was associated with a reduced risk of hepatocellular carcinoma (HCC) and hepatic decompensation; however, several methodologic limitations may have contributed to their findings.

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Publication Details

Journal
JAMA Internal Medicine
Published
2025-06-30
DOI
https://doi.org/10.1001/jamainternmed.2025.2207
Primary Topic
Cancer, Lipids, and Metabolism
Type
article
Field-Weighted Citation Impact
0.00
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article

Study Limitations in Statin Use and Risk of Hepatocellular Carcinoma

Ishak A.E. Mansi
1 links
JAMA Internal Medicine
Cancer, Lipids, and Metabolism
article

Study Limitations in Statin Use and Risk of Hepatocellular Carcinoma

Ishak A.E. Mansi
article en

Abstract

To the Editor I read with interest the study of Choi et al1 showing that statin use was associated with a reduced risk of hepatocellular carcinoma (HCC) and hepatic decompensation; however, several methodologic limitations may have contributed to their findings.

JAMA Internal MedicineVol. 185(9)
Orlando Health (US)
Openalex Percentile: Top 79%
Cancer, Lipids, and Metabolism
DOISourceOpenAlex
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Study Limitations in Statin Use and Risk of Hepatocellular Carcinoma — Ishak A.E. Mansi · JAMA Internal Medicine (2025) | TGRS Research Map | TGRS