Retention in Opioid Agonist Therapy Among First Nations People

This cohort study among First Nations people found low rates of OAT retention. Although retention was higher for methadone, it declined over time. These findings highlights important gaps in OAT provision for First Nations people that may be improved by investments into First Nations-led treatment programs that integrate traditional, land-based programs to better support people with opioid use disorder across Ontario.

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Publication Details

Journal
JAMA Network Open
Published
2025-06-30
DOI
https://doi.org/10.1001/jamanetworkopen.2025.18452
Citations
4
Primary Topic
Opioid Use Disorder Treatment
Type
article
Field-Weighted Citation Impact
7.51
Controls
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article

Retention in Opioid Agonist Therapy Among First Nations People

Graham Mecredy, Tonya Campbell, Alice Holton, Tara Gomes et al.
4 citations
JAMA Network Open
Opioid Use Disorder Treatment
7.51
article

Retention in Opioid Agonist Therapy Among First Nations People

Graham Mecredy, Tonya Campbell, Alice Holton, Tara Gomes, Tony Antoniou, Lorrilee McGregor, Sacha Bragg, Jonathan Bertram, Daniel McCormack, Bisola Hamzat, Bernadette deGonzague
article en
4 citations

Abstract

This cohort study among First Nations people found low rates of OAT retention. Although retention was higher for methadone, it declined over time. These findings highlights important gaps in OAT provision for First Nations people that may be improved by investments into First Nations-led treatment programs that integrate traditional, land-based programs to better support people with opioid use disorder across Ontario.

JAMA Network OpenVol. 8(6)
St. Michael's Hospital (CA), Centre for Addiction and Mental Health (CA), Royal College of Surgeons in Ireland (IE), University of Toronto (CA), Institute for Clinical Evaluative Sciences (CA), Unity Health Toronto, NOSM University (CA)
Sustainable cities and communities
Openalex Percentile: Top 3%
Opioid Use Disorder Treatment
7.51
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Retention in Opioid Agonist Therapy Among First Nations People — Graham Mecredy, Tonya Campbell, et al. · JAMA Network Open (2025) | TGRS Research Map | TGRS