Reflux Recurrence After Laparoscopic Fundoplication for Nonerosive Gastroesophageal Reflux Disease

This cohort study of patients who underwent primary laparoscopic fundoplication suggests that the risk of reflux recurrence was similar among patients with nonerosive GERD and those with erosive GERD. This finding is in contrast with evidence showing that nonerosive GERD responds less well to antireflux medication. Thus, the absence of erosive GERD detected by an upper endoscopy may not be used as an argument for abstaining from antireflux surgery.

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Publication Details

Journal
JAMA Network Open
Published
2025-06-30
DOI
https://doi.org/10.1001/jamanetworkopen.2025.17754
Primary Topic
Gastroesophageal reflux and treatments
Type
article
Field-Weighted Citation Impact
0.00

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article

Reflux Recurrence After Laparoscopic Fundoplication for Nonerosive Gastroesophageal Reflux Disease

Giola Santoni, Joonas H. Kauppila, Dag Holmberg, Jesper Lagergren et al.
JAMA Network Open
Gastroesophageal reflux and treatments
article

Reflux Recurrence After Laparoscopic Fundoplication for Nonerosive Gastroesophageal Reflux Disease

Giola Santoni, Joonas H. Kauppila, Dag Holmberg, Jesper Lagergren, My von Euler‐Chelpin, Eivind Ness‐Jensen, J Bielik
article en

Abstract

This cohort study of patients who underwent primary laparoscopic fundoplication suggests that the risk of reflux recurrence was similar among patients with nonerosive GERD and those with erosive GERD. This finding is in contrast with evidence showing that nonerosive GERD responds less well to antireflux medication. Thus, the absence of erosive GERD detected by an upper endoscopy may not be used as an argument for abstaining from antireflux surgery.

JAMA Network OpenVol. 8(6)
University of Copenhagen (DK), Karolinska University Hospital (SE), King's College London (GB), Norwegian University of Science and Technology (NO), Oulu University Hospital (FI), Levanger Hospital (NO), Karolinska Institutet (SE), University of Oulu (FI)
Cancerfonden, Vetenskapsrådet
No poverty
Openalex Percentile: Top 77%
Gastroesophageal reflux and treatments
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