Recurrence After Gallbladder Cancer Resection: Prognostic Impact of CA19‐9 and CEA Levels at Baseline and During Surveillance
Elevation of both preoperative CA19-9 and CEA levels portended poor prognosis following resection of GBC. Normalization of postoperative CA19-9 levels after GBC resection was still associated with elevated risk of recurrence. While preoperative tumor markers can accurately predict prognosis following resection for GBC, evaluation of traditional tumor markers may not be appropriate markers of occult recurrent disease in the postoperative setting. Better markers are needed to monitor for recurrence following resection of GBC.
Authors
- Thomas J. Hugh (ORCID: https://orcid.org/0000-0001-6690-342X)
- Andrea Ruzzenente (ORCID: https://orcid.org/0000-0001-6911-563X)
- Shishir K. Maithel (ORCID: https://orcid.org/0000-0002-3591-8925)
- Nazim Bhimani (ORCID: https://orcid.org/0000-0003-3995-4285)
- Federico Aucejo (ORCID: https://orcid.org/0000-0001-7841-229X)
- Itaru Endo (ORCID: https://orcid.org/0000-0001-5520-8114)
- Minoru Kitago
- Diamantis I. Tsilimigras (ORCID: https://orcid.org/0000-0002-3676-9263)
- Timothy Michael Pawlik (ORCID: https://orcid.org/0000-0002-7994-9870)
- João Pedro Bandovas (ORCID: https://orcid.org/0000-0001-9470-3193)
- Hugo P. Marques (ORCID: https://orcid.org/0000-0003-3540-0488)
- Odysseas P Chatzipanagiotou
Institutions
- University of Verona (IT)
- The University of Sydney (AU)
- Cleveland Clinic (US)
- Emory University (US)
- Keio University (JP)
- The Ohio State University Wexner Medical Center (US)
- Hospital Curry Cabral (PT)
- Yokohama City University (JP)
Publication Details
- Journal
- Journal of Surgical Oncology
- Published
- 2025-06-30
- DOI
- https://doi.org/10.1002/jso.70024
- Primary Topic
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00