A three-country analysis of the gut microbiome indicates taxon associations with diet vary by taxon resolution and population
An analysis of fecal microbiome data from individuals in the United States, United Kingdom, and Mexico shows that associations with dietary components vary both by country and by level of resolution (i.e., genus and strain). Our work sheds light on why there may be conflicting reports regarding microbial associations with diet, disease, and health.
Authors
- Nicole S. Litwin
- Se Jin Song (ORCID: https://orcid.org/0000-0003-0750-5709)
- Nimbe Torres (ORCID: https://orcid.org/0000-0002-1741-0984)
- MacKenzie Bryant (ORCID: https://orcid.org/0000-0003-0749-2995)
- Charles Cowart (ORCID: https://orcid.org/0009-0002-6741-8914)
- Sudarshan Anand Shetty (ORCID: https://orcid.org/0000-0001-7280-9915)
- Lora A. Khatib (ORCID: https://orcid.org/0000-0002-6998-8278)
- Patrick Veiga (ORCID: https://orcid.org/0000-0001-6318-8547)
- Antonio González (ORCID: https://orcid.org/0000-0001-8380-0270)
- Caitlin Tribelhorn (ORCID: https://orcid.org/0009-0002-8788-471X)
- Muriel Derrien (ORCID: https://orcid.org/0000-0001-8841-9153)
- Andrew P. Bartko (ORCID: https://orcid.org/0000-0002-1237-2747)
- Rob Knight (ORCID: https://orcid.org/0000-0002-0975-9019)
- Soline Chaumont (ORCID: https://orcid.org/0000-0002-4084-6057)
- Sawyer H. Farmer (ORCID: https://orcid.org/0009-0006-4160-9535)
- Promi Das (ORCID: https://orcid.org/0000-0001-6733-2059)
- Aurélie Cotillard (ORCID: https://orcid.org/0009-0004-7409-7703)
- Axel Hernández (ORCID: https://orcid.org/0000-0003-3720-2856)
- Guus Roeselers (ORCID: https://orcid.org/0000-0002-4725-6105)
- Amanda Birmingham (ORCID: https://orcid.org/0000-0002-4117-3317)
- Hana Koutníková (ORCID: https://orcid.org/0000-0001-7763-8983)
- Caitriona Brennan (ORCID: https://orcid.org/0000-0003-3943-6701)
- Amanda Hazel Dilmore (ORCID: https://orcid.org/0000-0001-6493-7116)
- Jan Knol (ORCID: https://orcid.org/0000-0002-2103-5961)
- Kat Gilbert
- Jon G. Sanders (ORCID: https://orcid.org/0000-0001-6077-4014)
- Manolo Laiola
- Armando R. Tovar (ORCID: https://orcid.org/0000-0002-1292-1312)
- Brent Nowinski (ORCID: https://orcid.org/0000-0002-6847-8145)
- Julien Tap (ORCID: https://orcid.org/0000-0001-8998-5413)
- Renee Oles (ORCID: https://orcid.org/0000-0001-5945-0215)
- Edgar A. Diaz (ORCID: https://orcid.org/0000-0002-9076-6549)
- Daniel McDonald
- Oliver Nizet
- Karenina Sanders-Bodai
- Liliana Arteaga
- Christophe Lay
- Tyler Myers (ORCID: https://orcid.org/0009-0008-3141-1220)
Institutions
- Johns Hopkins University (US)
- University of California San Diego (US)
- Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán (MX)
- Danone (Morocco) (MA)
- Crohn's and Colitis Foundation (US)
- Wageningen University & Research (NL)
Publication Details
- Journal
- mSystems
- Published
- 2025-06-30
- DOI
- https://doi.org/10.1128/msystems.00544-25
- Citations
- 5
- Primary Topic
- Gut microbiota and health
- Type
- article
- Field-Weighted Citation Impact
- 4.03
Funders
- Danone
- Danone Nutricia Research